] ASCP-MLT Learning Materials: MEDICAL LABORATORY TECHNICIAN - MLT(ASCP) - ASCP-MLT Actual Lab Questions

ASCP MEDICAL LABORATORY TECHNICIAN - MLT(ASCP) : ASCP-MLT

  • Exam Code: ASCP-MLT
  • Exam Name: MEDICAL LABORATORY TECHNICIAN - MLT(ASCP)
  • Updated: Jun 05, 2026
  • Q & A: 562 Questions and Answers

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ASCP MEDICAL LABORATORY TECHNICIAN - MLT(ASCP) Sample Questions:

1. When making a platelet concentrate, the proper procedure is to start with a low centrifugation of the whole blood bag. After the plasma is removed, it is centrifuged again at a higher speed to separate the platelet portion from the plasma portion.
Blood bank
The following steps must be followed in preparation of a platelet concentrate:

A) Whole blood centrifuged at low speed - plasma separated then centrifuged at low speed
B) Whole blood centrifuged at high speed - plasma separated then centrifuged at low speed
C) Whole blood centrifuged at low speed - plasma separated then centrifuged at high speed
D) Whole blood centrifuged at high speed - plasma separated then centrifuged at high speed


2. Laboratories performing which of the following types of tests need to be enrolled in a CLIA-approved proficiency testing program?

A) Moderately complex
B) Waived
C) Highly complex
D) both moderately and highly complex


3. The two main areas of the clinical laboratory are:

A) chemistry and hematology.
B) cytology and histology.
C) urinalysis and microbiology.
D) anatomical and clinical.


4. This patient is most likely suffering from sickle cell anemia. This cell, which is sickle-shaped, is indicative of the presence of hemoglobin S. Polychromasia is also commonly observed in sickle cell anemia.
After experiencing crippling pain in her chest, Elizabeth's mother rushes her to the Emergency Room. After a complete blood count and differential are ordered, the hematology technologist views many peripheral cells similar in appearance to those found in the image below. Which condition is most likely present?

A) hemoglobin c disease
B) sickle cell anemia
C) myocardial infarction
D) beta thalassemia


5. Hemoglobin H is a tetramer made of four beta globin chains. Hemoglobin H occurs when there is very limited alpha chain availability used to make normal hemoglobin A. Hemoglobin H forms in those affected with alpha thalassemia major as well as in people with the combination of two-gene deletion alpha thalassemia and hemoglobin Constant Spring.
Hematology
Which of the following combination of globin chains comprise Hemoglobin H?

A) 4 beta chains
B) 4 alpha chains
C) 2 alpha, 2 beta
D) 2 alpha, 2 gamma


Solutions:

Question # 1
Answer: C
Question # 2
Answer: D
Question # 3
Answer: D
Question # 4
Answer: B
Question # 5
Answer: A

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